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19. Poster Session
Assay Development: Neutralizing Antibodies

Abstracts

#Title
79 A Rapid Multi-Functional HIV-1 Entry Assay for Measuring Neutralizing Antibody, Coreceptor Tropism, and Drug Susceptibility
T. Wrin, W. Huang, J. Yap, S. Fransen, J. Beauchaine, N. Whithurst, M. Reddy, S. Nidtha, E. E. Paxinos, N. T. Parkin, J. W. Whitcomb, and C. J. Petropoulos*
ViroLogic, Inc., South San Francisco, CA, USA

80 Rapid Screening of Subtype B and C Neutralizing Antibody Response against PBMC-Grown HIV-1 Isolates in Engineered CEM Cell Line
Y. Sun*1, N. Laudau2, T. Brown, and S. Susan1
1Chiron Corp., Emeryville, CA, USA and 2Aaron Diamond AIDS Res. Ctr., New York, NY, USA

81 Characteristics of Anti-HIV-1 Antibody Binding and HIV-1 Envelope Glycoprotein on Infected Lymphocytes
G. Gorse*1,2, G. Patel2, R. Belshe2, and the NIAID HIV Vaccine Trials Network
1VA Med. Ctr. and 2St. Louis Univ., MO, USA

82 Binding and Neutralization of Primary Isolates by IgG of Infected Patients
R. Burrer, S. Haessig, V. Roques, A.-M. Aubertin, and C. Moog*
Inst. de Virologie, Strasbourg, France

83 Candidate HIV-1 Vaccines Induce Antibodies That Neutralize in Vitro Primary Isolates in Assays with Extended Incubation Phases
H. Donners*, D. Davis, B. Willems, T. Vermoesen, and G. van der Groen
Inst. of Tropical Med., Antwerp, Belgium

84 Improved Measurement of Antibody-Mediated Neutralization of HIV-1 by Flow Cytometric Enumeration of Infected T Cells
J. Mascola1*, M. Louder1, C. Winter1, D. Gabuzda2, and M. Roederer1
1Vaccine Res. Ctr., NIAID, NIH, Bethesda, MD, USA and 2Dana-Farber Cancer Inst., Boston, MA, USA

85 Absorption Studies Probing the Target of Primary Virus Neutralization
M. Trahey*, S. Larson, K. Follis, and J. Nunberg
Univ. of Montana, Missoula, USA