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26. Poster Session
Determinants of HIV Disease Progression

Abstracts

#Title
134 NFAT Is a Determining Factor in Preferential HIV-1 Replication of CD45RO-Expressing CD4+ T Cells
G. A. Robichaud*1, B. Barbeau1, J.-F. Fortin1, D. M. Rothstein2, and M. J. Tremblay1
1Univ. Laval, Québec, PQ, Canada and 2Yale Univ., New Haven, CT, USA

135 Presentation of HIV gp120 Antigen to CD4 T-Helper Cells Is Prevented by Antibodies
P. Chien, Jr.1, M. Tuen1, P. D. Chen1, S. Cohen1, C. Kleeberger2, J. Giorgi3, J. Phair4, S. Zolla-Pazner1, and C. E. Hioe*1
1New York Univ. and VA Med Ctrs, NY, USA; 2Johns Hopkins Sch. of Publ. Hlth., Baltimore, MD, USA; 3UCLA Med. Sch., Los Angeles, CA, USA; and 4Northwestern Med. Sch., Chicago, IL, USA

136 Why Antigen-Specific CD8 T Lymphocytes Fail to Prevent Progressive Immunodeficiency in HIV-1 Infection
J. Andersson1, K. Lore1, A. Sonnerborg1, L. Perrin2, D. Cooper3, B. Gazzard4,S. Kinloch4, R. Weber5, H. Stellbrink6, C. Tsoukas7, G. Tambussi8, and L. Goh9
Depts. of Inf. Diseases, 1Sweden, 2Geneva, 3Australia, 4London, 5Zurich, 6Hamburg, 7Montreal, 8Milan, and 9GlaxoSmithKline

137 In Vivo Expression of Cytokines and Chemokines and HIV-1 Disease Progression: Role of HTLV-II Coinfection
E. Vicenzi*1, C. Casoli2, S. Ghezzi1, U. Bertazzoni3, and G. Poli1
1San Raffaele Scientific Inst., Milan, Italy; 2Univ. of Parma, Italy; and 3Univ. of Verona, Italy

138 Evolution of Promoter Activities of Attenuated Strains of HIV-1
M. J. Churchill*, I. de Castella, D. Rhodes, D. McPhee, and N. Deacon
Macfarlane Burnet Ctr. for Med. Res., Fairfield, Victoria, Australia

139 First Evidence Showing Absence of in Vivo Evolution in HIV-1 over Time: Implications for HIV Vaccine Development
B. Wang*, M. Mikhail, and N. K. Saksena
CVR, Westmead Millennium Inst., Westmead Hosp., Univ. of Sydney, Sydney, NSW, Australia

140 Predictors of Disease Progression in LTNP: A 5-Year Follow-Up Study
E. Vicenzi1, S. Ghezzi1, G. Vallanti1, F. Neri1, D. Douek2, E. Santagostino3, A. Gringeri3, M. Cusini3, A. Lazzarin1, F. Veglia4, and G. Poli*1
1San Raffaele Scientific Inst., Milano, Italy; 2Vaccine Res. Ctr., NIH, Bethesda, MD, USA; and 3IRCCS Maggiore Hosp., Milano, Italy

141 Immune Correlates of HIV-1 Disease Progression in Subtype E-Infected Thais
T. Chuenchitra*1, C. Wasi2, S. Louisirirotchanakul2, M. de Souza1, S. Nitayaphan1, R. Sutthent2, A. Brown1, D. Birx3, and V. Polonis3
1AFRIMS, Bangkok, Thailand; 2Siriraj Hosp. Bangkok, Thailand; and 3US Military HIV Res. Program, Rockville, MD, USA

142 Plasma SDF-1 Levels, SDF1-3A Genotype, and CXCR4 Expression on T Lymphocytes: Their Influence on Resistance to HIV-1 Infection and Its Progression
A. Soriano*1, C. Martinez1, E. Palou1, F. García1, M. Plana1, J. M. Aróstegui1, M. Lejeune1, J. del Romero2, C. Rodriguez2, A. Barrasa2, J. I. Lorenzo3 , J. M. Miró1, J. M. Gatell1, and T. Gallart1
1Hosp. Clin., Barcelona, Spain; 2Centro Médico Sandoval, Madrid, Spain; and 3Hosp. La Fe, Valencia, Spain