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34. Poster Session
DNA Vaccines

Abstracts

#Title
180 Dying to Produce a Lively HIV Vaccine: HIV DNA Vaccines Improving Antigen Delivery to Dendritic Cells through Apoptosis in Vivo Results in Improved Cellular Immunity
M. A. Chattergoon, J. J. Kim, J.-S. Yang, J. I. Sin, S. Kudchodkar, and D. B. Weiner*
Univ. of Pennsylvania Sch. of Med. and Viral Genomix, Philadelphia, USA

181 Enhanced Humoral Immune Responses Elicited by DNA Vaccination with HIV gp120-C3d Fusion Constructs
T. Ross*1, T. Green1, Y. Xu2, D. Montefiori3, and H. Robinson2
1East Carolina Univ., Greenville, NC, USA; 2Emory Univ., Atlanta, GA, USA; and 3Duke Univ., Durham, NC, USA

182 Enhancement of Immune Responses with a DNA Vaccine Construct That Targets APCs
W. Zhang*, Z. Chen, Y. Huang, and D. D. Ho
Aaron Diamond AIDS Res. Ctr., The Rockefeller Univ., New York, NY, USA

183 Induction of Potent Immune Responses by Cationic Microparticles with Adsorbed HIV DNA Vaccines
M. Briones*1, D. O'Hagan1 , M. Singh1, M. Ugozzoli1, C. Wild2, S. Barnett1, M. Chen1, G. R. Otten1, and J. B. Ulmer1
1Chiron Corp., Emeryville, CA, USA and 2Panacos Pharmaceuticals, Gaithersburg, MD, USA

184 HIV Gag DNA Vaccine: Mutation in the Gag Increases Its Immunogenicity
H. Zhang and L. Qiao*
Loyola Univ. Chicago, Maywood, IL, USA

185 Attenuated HIV-1 nef DNA Vaccine Construct Induces Memory T-Cell Response
B. Majumdar1, B. Gray1, S. Mahalingam2, S. McBurney1, T. Schaefer1, T. Dentchev3, T. Reinhart1, and V. Ayyavoo*1
1Univ. of Pittsburgh Graduate Sch. of Publ. Hlth., PA, USA; 2Ctr. for DNA Fingerprinting and Diagnostics, Hydrabad, India; and 3Univ. of Pennsylvania, Philadelphia, USA

186 Immunological Properties of HIV-1 env Gene-Based DNA Vaccines
B. V. Murashev*, I. V. Murasheva, T. Y. Kreslavskiy, A. E. Romanovitch, N. A. Klimov, and A. P. Kozlov
Biomedical Ctr., St. Petersburg, Russia

186a Prime-Boost Immunisation Leads to the Development of a Persistent, High Avidity CD8 T-Cell Population
M. J. Estcourt1, A. Brookes2, A. J. Ramsay3, S. A. Thomson1, C. J. Medveckzy1, and I. A. Ramshaw*1
1John Curtin Sch. of Med. Res., Australian Natl. Univ., Canberra; 2Univ. of Melbourne, Australia; and 3Ctr. for Biomolecular Vaccine Technology, Univ. of Newcastle, Australia