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LB1 Stochastic Simulation to Assess Vaccine Impact on HIV Incidence in Rakai, UgandaView Abstract
R. Gray*1, X. Li1, M. Wawer2, R. Moore1, D. Serwadda3, N. Sewankambo3, F. Wabwire-Mangen3, T. Lutalo4, and T. Quinn1
1Johns Hopkins Univ., Baltimore, MD, USA; 2Columbia Univ., Sch. of Publ. Hlth., New York, NY, USA; 3Makerere Univ., Sch. of Med., Kampala, Uganda; and 4Rakai Project, Entebbe, Uganda
LB2 Use of T-Cell Costimulatory Blockade during Acute SIV Infection of Rhesus Macaques to Define the Relative Importance of Cellular and Humoral Immune Responses in Control of Viremia and Disease ProgressionView Abstract
D. A. Garber1, G. Silvestri1, A. Fedanov1, R. Regos1, A. Barry1, N. Kozyr1, C. P. Larsen1, H. McClure1, D. Montefiori2, J. D. Altman1, S. Staprans1, and M. B. Feinberg*1
1Emory Vaccine Res. Ctr., Atlanta, GA, USA and 2Duke Univ., Durham, NC, USA
LB3 Dynamics of HIV-1 Immune Control and EscapeView Abstract
G. Shaw*1, X. Wei1, N. Jones2, M. Saag3, B. Korber4, M. Nowak5, and P. Borrow2
1Howard Hughes Med. Inst., Birmingham, AL, USA; 2Edward Jenner Inst. for Vaccine Res., Compton, UK; 3Univ. of Alabama at Birmingham, USA; 4Los Alamos Natl. Labs, NM, USA; and 5IAS, Princeton, NJ, USA
LB4 High Frequency of Virus-Specific B Lymphocytes in Germinal Centers of SHIV-Infected Rhesus MonkeysView Abstract
D. Margolin*1, E. Helmuth2, B. Bronfin1, N. de Rosa1, M. Axthelm3, X. Alvarez4, and N. Letvin1
1Beth Israel Deaconess Med. Ctr., Harvard Med. Sch., Boston, MA, USA; 2Univ. of Iowa Coll. of Med., Iowa City, USA; 3Oregon Regional Primate Res. Ctr., Oregon Hlth. Sci. Univ., Beaverton, USA; and 4New England Regional Primate Res. Ctr., Harvard Med. Sch., Southborough, MA, USA
LB5 Merck's HIV Vaccine Program: Research Approaches and Critical IssuesView Abstract
John Shiver
Merck Research Laboratories, West Point, PA, USA